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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: OPLAH All Species: 16.97
Human Site: T639 Identified Species: 33.94
UniProt: O14841 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14841 NP_060040.1 1288 137457 T639 D D V R V R G T G R S G L R L
Chimpanzee Pan troglodytes XP_528261 1212 130154 A605 A T A R S P R A G D F G A A F
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_539206 1379 147579 T736 D D V R V R G T G R S G L R L
Cat Felis silvestris
Mouse Mus musculus Q8K010 1288 137593 T639 D D V R V R G T G R S G L Q L
Rat Rattus norvegicus P97608 1288 137702 T639 D D V R V R G T G R S G L Q L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521030 1300 139318 G651 N V R V R G K G I S G L D P E
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611675 1294 139594 G642 D I R I R G L G K N E T P P E
Honey Bee Apis mellifera XP_001121487 1287 139635 T639 N D V R I R G T G T T D I E Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_794494 1307 142838 V648 D D I R V R G V G K T F I P L
Poplar Tree Populus trichocarpa XP_002305860 1269 137853 V645 V R V R G I G V T N I L K P Q
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FIZ7 1266 137512 V641 V R V R G I G V T S I L K P R
Baker's Yeast Sacchar. cerevisiae P28273 1286 140409 Q652 K E K T V D E Q L I E I S H F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 92.5 N.A. 69.4 N.A. 92.5 93.9 N.A. 80.2 N.A. N.A. N.A. N.A. 61.2 65 N.A. 64.1
Protein Similarity: 100 93.1 N.A. 74 N.A. 95.6 96.1 N.A. 87.2 N.A. N.A. N.A. N.A. 74.5 76.9 N.A. 76.1
P-Site Identity: 100 20 N.A. 100 N.A. 93.3 93.3 N.A. 0 N.A. N.A. N.A. N.A. 6.6 46.6 N.A. 53.3
P-Site Similarity: 100 20 N.A. 100 N.A. 100 100 N.A. 6.6 N.A. N.A. N.A. N.A. 6.6 73.3 N.A. 80
Percent
Protein Identity: 57.2 N.A. N.A. 56.8 49 N.A.
Protein Similarity: 70.9 N.A. N.A. 71.2 66 N.A.
P-Site Identity: 20 N.A. N.A. 20 6.6 N.A.
P-Site Similarity: 20 N.A. N.A. 20 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 9 0 0 0 0 9 0 0 0 0 9 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 50 50 0 0 0 9 0 0 0 9 0 9 9 0 0 % D
% Glu: 0 9 0 0 0 0 9 0 0 0 17 0 0 9 17 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 9 9 0 0 17 % F
% Gly: 0 0 0 0 17 17 67 17 59 0 9 42 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % H
% Ile: 0 9 9 9 9 17 0 0 9 9 17 9 17 0 0 % I
% Lys: 9 0 9 0 0 0 9 0 9 9 0 0 17 0 0 % K
% Leu: 0 0 0 0 0 0 9 0 9 0 0 25 34 0 42 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 17 0 0 0 0 0 0 0 0 17 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 9 0 0 0 0 0 0 9 42 0 % P
% Gln: 0 0 0 0 0 0 0 9 0 0 0 0 0 17 17 % Q
% Arg: 0 17 17 75 17 50 9 0 0 34 0 0 0 17 9 % R
% Ser: 0 0 0 0 9 0 0 0 0 17 34 0 9 0 0 % S
% Thr: 0 9 0 9 0 0 0 42 17 9 17 9 0 0 0 % T
% Val: 17 9 59 9 50 0 0 25 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _